This is the largest long-term study of women who carry a mutation in one of the two breast cancer genes (BRCA1/BRCA2). This study was started in 1995 by Dr. Steven Narod and now has upwards of 16,000 participants from across Canada, the United States, Europe, and Asia. Its purpose is to better understand the prevention and treatment of hereditary breast and ovarian cancers. We hope to gain a better understanding of the interaction between various hormonal, reproductive, and lifestyle factors that may be associated with the development of breast and ovarian cancer in high-risk families. Click here to view the Investigators Brochure.
Learn more about some of the important findings that have come from Dr. Narod's studies.
Who Can Participate?
Why Should You Participate?
The risk of breast and ovarian cancer in carriers of BRCA1 or BRCA2 mutations is believed to be influenced by several genetic and non-genetic factors. A bigger study population will produce more accurate results, giving you an opportunity to make better decisions regarding your health.
What Does Participation Entail?
To participate, all we need you to do is to fill a questionnaire that asks questions about your health, menstrual cycle, lifestyle, etc. every two years. You may stop participation at any time. We estimate that the questionnaire could take about 30 minutes to complete.Jump to top page
How to participate
Click here to download a request form in Word
You may also call or email us to request a package or to receive more information before making your decision.
Phone: (416) 351-3765 or
Risk Factor Analysis of Hereditary Breast and Ovarian Cancer